Up-to-date evidence-based information on emerging vaccines in pregnancy and childhood

A regularly updated, comprehensive database and synthesis of published literature related to COVID-19 vaccines in pregnancy through a living systematic review and meta-analyses.

Supported by the Bill & Melinda Gates Foundation (INV-008443)

Vaccine vial
mosquito Aedes aegypti
Mother children chikungunya

A continuously updated, thorough compilation and analysis of published and unpublished literature concerning Chikungunya vaccines during pregnancy and childhood through a living systematic review and meta-analyses.

Summary of findings

Supported by the Safety Platform for Emergency vACcines (SPEAC), Task Force for Global Health, Inc. – The Coalition for Epidemic Preparedness Innovations (CEPI).

An ongoing, comprehensive review and analysis of published literature on safety, efficacy, effectiveness and immunogenicity of Mpox vaccines during pregnancy and childhood, utilizing a living systematic review and meta-analysis approach.

Pairwise and Proportional Meta Analyses
PRISMA Flow Diagram
Summary of findings
Quality Assessment

Supported by the Safety Platform for Emergency vACcines (SPEAC), Task Force for Global Health, Inc. – The Coalition for Epidemic Preparedness Innovations (CEPI).

Monkeypox lesions in the thigh of Asian, Burmese Child
mpox vaccination
Boy showing younger brother plaster on arm
woman baby Kenya

An ongoing, comprehensive collection and examination of published and unpublished literature on Chikungunya vaccines during pregnancy and childhood, with regular updates through a living systematic review and meta-analyses.

Pairwise Meta Analysis
Summary of findings
Proportional Meta Analyses
Quality Assessment
Summary Table
PRISMA Flow Diagram

Supported by the Safety Platform for Emergency vACcines (SPEAC), Task Force for Global Health, Inc. – The Coalition for Epidemic Preparedness Innovations (CEPI).

vaccine vial disease x
Woman and man doctors

Disease X is the name given by scientists to an unknown pathogen that could emerge in future and cause a serious international epidemic or pandemic. Disease X is included in the WHO’s updated Blueprint list of diseases for which investing in research and development should be an international
priority. It is also a priority for CEPI’s research and development investments.

Our living systematic review will provide up-to-date information on platforms and components
of vaccines used in pregnancy and childhood which could potentially be adapted to develop
new vaccines against Disease X. We will also be ready to rapidly deploy a living systematic
review of future vaccines against Disease X to protect pregnant people and children.

Get In Touch with Us

Andrea Meyer

Director of Global Health Research